Resistance

Mechanisms of Resistance

There are a number of ways insects can become resistant to insecticidal crop protection and public health products:

  • Metabolic resistance. Using enhanced levels of metabolism by enzymes, resistant insects may detoxify a particular insecticide faster than susceptible insects, and quickly rid their bodies of the insecticidal compounds.
  • Target-site resistance. The target site where the insecticide acts in the insect may be genetically modified to prevent the insecticide binding or interacting at its site of action thereby reducing or eliminating the pesticidal effect of the insecticide.
  • Penetration resistance. The insecticide may penetrate through the cuticle of resistant insects more slowly than susceptible insects. 

  • Behavioural resistance. Resistant insects may detect or recognize the presence of the insecticide and avoid it.

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