The IRAC Mode of Action Classification

The definitive, global authority on the target site of insecticides.

The IRAC Mode of Action (MoA) Classification is the basis of MoA labelling of insecticides worldwide. It is an essential tool for the development and delivery of insecticide resistance management (IRM) strategies around the world.

Browse the classification

  • Browse online now

    The MoA Classification is available as an interactive searchable eTool allowing you to browse and filter chemical groups, classes and actives.

  • Get the classification to go

    Download the IRAC MoA application from the Apple iTunes or Google Play App Stores for quick access to reference information on the move.

    Please visit the relevant app store:

  • Print the MoA Structures Poster

    The MoA poster with the chemical structures is available for download from the website in various languages including Chinese & Japanese!

  • Download the Classificaiton Scheme in PDF

    The complete MoA Classification document is available to view or download. This 23-page document provides full details of the scheme with lots of supplimentary information and guidance.

Keep up to date

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    Subscribe to receive a notification when IRAC updates the Mode of Action Classification.

  • Submit an active

    Submit an active you think should be included in IRAC’s Mode of Action Classification.

  • View the MoA video

    Our team of technical experts are charged with maintaining the classification and it’s status.

  • Meet the team and see more resources

    Review all of our Mode of Action documentation.

The IRAC MoA Classification


Modes of action are colour-coded according to the physiological functions affected. This informs the symptomology, speed of action and other properties of the actives therein and not for any resistance management purpose.

Rotations for resistance management should be based only on the numbered mode of action groups.

Learn more about mode of action and resistance management.

  • Nerve & Muscle
  • Growth
  • Respiration
  • Midgut
  • Unknown or Non-Specific